The purpose of the Terms is to establish the rights and obligations of Psomagen and Client with respect to Psomagen's service or product as requested or ordered by Client. Psomagen and Client shall faithfully perform their duties as specified in these Terms.
Unless specified otherwise in these Terms, the following terms have the meanings set forth herein.
These Terms shall become effective as of the date when Client places an order and shall remain in full force and effect till the completion date unless agreed otherwise.
Service name | Samples and Primers | data |
---|---|---|
CES | 30 days | 3 years |
NGS | 3 months | 3 months |
Clinical | 3 months | 3 months |
Nanopore SEQ | 30 days | 3 months |
After placing an order, Client may request and receive additional technical support or consulting service from Psomagen. In the event that such support or service incur any additional costs, Psomagen shall notify and discuss with the client in advance.
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Primer |
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Psomagen provides various gene analysis services using precise DNA microarray technology.
Known by various terms such as DNA chip, biochip and gene-array, microarray is a technology
that measures the expression pattern of genes and verifies whether there is a mutation
by arranging invisible probes on a chip and reacting DNA, RNA, protein, etc.
Psomagen is the only company in Korea that has all the products of Illumina, Affymetrix and Agilent,
which are the main suppliers of microarray products. Based on such equipment,
we offer genetic testing services for research purposes such as mRNA, miRNA, SNP, CGH
and DNA methylation.
With an mRNA expression microarray, tests are performed for the mRNA analysis of various organisms
and significant genes can be selected by conducting a statistical analysis of the data obtained from the tests.
Manufacturer | Specimen | Platform |
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Agilent |
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Affymetrix |
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Life Technologies |
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Analysis Items | Contents |
---|---|
Affymetrix | Basic statistics(Fold change, group mean, sd etc.) |
Identifying differentially expressed genes(T-test, LPE test, ANOVA etc.) | |
Multiple testing correction (FDR, Bonferroni etc.) | |
Clustering Analysis for DEG ( Hierarchical clustering, K-means etc.) | |
Functional analysis | KEGG pathway, GeneOntologyannotation(DAVID, goProfiles, GOstats etc.) |
GeneSet Enrichment Analysis | |
Customized analysis | Integrative analysis (mRNA-miRNA, methylation~mRNA, mRNA-CNV etc.) |
microRNAs exist in many forms according to the generation process.
We have many microarray products to analyze the expression patterns of mature miRNAs known by studies.
Psomagen provides analysis services including selection of microRNAs where differential expression is confirmed
and target mRNA prediction, as well as test services using microarrays.
Manufacturer | Specimen | Platform |
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Agilent |
|
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Affymetrix |
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|
Life Technologies |
|
Analysis Items | Contents |
---|---|
Data analysis of DE | Basic statistics(Fold change, group mean, sd etc.) |
Identifying differentially expressed genes(T-test, LPE test, ANOVA etc.) | |
Multiple testing correction (FDR, Bonferroni etc.) | |
Clustering Analysis for DEG ( Hierarchical clustering, K-means etc.) | |
Customized analysis | Target gene prediction |
Integrative analysis (mRNA-miRNA) |
For human genome composed of about 3 billion pairs of bases, most DNA sequences of individuals match,
but about 0.1% is SNP (Single Nucleotide Polymorphism), which is where the difference lies.
Research institutes and medical institutions around the world are actively conducting research to define the functional characteristics of SNP.
With various kinds of microarrays, Psomagen can easily provide analysis for hundreds of thousands to millions of Human SNP.
Manufacturer | Specimen | Type | Platform | SNP contents |
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Illumina |
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Genome Wide SNP Array | Infinium Omni5Exome-4 | 4.5M |
Infinium Omni5-4 | 4.3M | |||
Infinium Omni2.5Exome-8 | 2.7M | |||
Infinium Omni2.5-8 | 2.5M | |||
Infinium OmniExpressExome-8 | 950K | |||
Infinium OmniExpress-24 | 715K | |||
Infinium Asian Screening Array | 660K | |||
Infinium GlobalScreeningArray | 660K | |||
Etc | ||||
Life Technologies |
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Openarray Customization | Up to 240 SNPs | |
Taqman genotyping |
Analysis Items | Contents |
---|---|
SNP analysis | SNP analysis |
Single Based Association Study (PLINK, R) | |
Gene Based Association Study (SKAT, Score-Seqetc) | |
Family based Association Study (TDT, FBAT) | |
Linkage analysis (Merlin) | |
CNV analysis | CNV segments Data (cnvPartition) |
CNVR association study | |
DGV mapping | |
Customized analysis | Additional plotting, annotation, etc.. |
CNV (Copy Number Variation) means the DNA variation that a certain sequence section
more than 1Kb is lost or amplified and repeated in the chromosome.
Such copy number variation can cause various genetic diseases as well as the proliferation of cancer cells.
Psomagen analyzes structure variation in chromosomes including CNV
using CGH (Comparative Genome Hybridization) microarray.
Products | No. of probes | Average marker spacing |
---|---|---|
Human CGH 1x1M | 1M | 3,118 base |
Human CGH 2x400K | 400K | 7,304 base |
Human CGH 4x180K | 180K | 17,627 base |
Human CGH 8x60K | 60K | 54,455 base |
Analysis items | Contents |
---|---|
CNV analysis | CNV segments Data (cnvPartition) |
CNVR association study | |
DGV mapping | |
Customized analysis | Additional plotting, annotation, etc.. |
DNA methylation is a chemical transformation that controls gene expression.
This phenomenon of methyl generated in cytosine at the CpG site exists around the promoter region of a gene.
Psomagen can correctly identify whether there is genome methylation using Illumina microarray
and give biological meaning with statistical analysis of the results.
Product | Contents | Feature |
---|---|---|
Infinium Methylation EPIC Bead Chip |
>860,000 CpG sites (>26,000 genes) |
* 8 samples are tested per chip Test on FFPE sample is available |
Analysis item | Contents |
---|---|
Data analysis of DM CpG | Basic statistics(delta_mean, group mean, sd etc.) |
Identifying differentially methylated CpGs(T-test, LPE test, ANOVA etc.) | |
Multiple testing correction (FDR, Bonferroni etc.) | |
Clustering Analysis for DM CpGs( Hierarchical clustering, K-means etc.) | |
Functional analysis | KEGG pathway, GeneOntologyannotation(DAVID, goProfiles, GOstats etc.) |
GeneSet Enrichment Analysis | |
Customized analysis | Integrative analysis (methylation~mRNA etc.) |
This agreement is a contract between you and Psomagen, Inc. (hereafter, Psomagen) and applies to Psomagen’s services usage in whole. You shall read, agree with and accept all of the terms and conditions contained in this agreement.
This agreement is to comply with the law of electric communication enterprise and an Enforcement Ordinance in the United States of America on the utilization stipulation and procedure of all the related services provided by Psomagen, Inc.
Service defines that it furnishes DNA sequencing and other additional information through https://order.psomagen.com to be provided by Psomagen, Inc. hereunder.
Psomagen can delete the notice posted by users for the following without any pre-notice.
All disputes, controversies or differences which may arise out of or in connection with the Contract or for the breach thereof shall be finally settled by arbitration in the USA in accordance with the Commercial Arbitration Rules of the USA.
The Contract shall be governed and interpreted by the laws of the USA.
Unless otherwise provided herein, Supplier shall not be liable for any consequential, direct or indirect damages, related to free service except for the damages caused by willful misconduct.
We are not liable for damage or losses to any of one’s standard sequencing result files which are stored in Psomagen’s server resulting from participation in or accessing or downloading file or data in connection with the Service.
We reserve the right, in our sole discretion, to cancel or suspend the Service should a virus, bugs, or other causes beyond our control corrupt the administration, security or proper operation of the Service.
You shall pay liquidated damages, not as a penalty, to Psomagen in an amount of 10% of the total amount of the delayed payment beyond the due date.